Polyamines and Hypusination Are Required for Ebolavirus Gene Expression and Replication
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منابع مشابه
Polyamines and Hypusination Are Required for Ebolavirus Gene Expression and Replication
UNLABELLED Ebolavirus (EBOV) is an RNA virus that is known to cause severe hemorrhagic fever in humans and other primates : EBOV successfully enters and replicates in many cell types. This replication is dependent on the virus successfully coopting a number of cellular factors. Many of these factors are currently unidentified but represent potential targets for antiviral therapeutics. Here we s...
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Ebolavirus (EBOV) is an enveloped, non-segmented, negative-stranded RNA virus, which consists of five species: Zaire ebolavirus, Sudan ebolavirus, Tai Forest ebolavirus, Bundibugyo ebolavirus, and Reston ebolavirus. EBOV causes a lethal hemorrhagic fever in both humans and non-human primates. The EBOV RNA genome encodes seven viral proteins: NP, VP35, VP40, GP, VP30, VP24, and L. VP40 is a matr...
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ژورنال
عنوان ژورنال: mBio
سال: 2016
ISSN: 2161-2129,2150-7511
DOI: 10.1128/mbio.00882-16